درباره
KPV is a synthetic peptide that has attracted attention for its potential anti-inflammatory and immunomodulatory effects. The product sold under the name "Buy KPV Peptide" typically comes in a 10 mg – 10 Vial Box, which means each vial contains 1 mg of the peptide, and there are ten vials in the package, totaling 100 mg. This format is convenient for researchers who need to run multiple experiments or for clinicians who wish to explore therapeutic dosing schedules. The peptide itself is a short tripeptide composed of the amino acids lysine (K), proline (P) and valine (V). It is often referred to as KPV because these are the one-letter codes for those residues. In many studies, KPV has been shown to inhibit neutrophil migration and reduce cytokine production, making it a candidate for treating inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, or even certain neuroinflammatory conditions.Description
The KPV peptide is manufactured under GMP (Good Manufacturing Practice) guidelines, ensuring high purity and consistency across batches. The typical specifications include a purity of 95% or higher, with an endotoxin level below the acceptable threshold for in vivo use. Each vial is provided as a lyophilized powder that can be reconstituted with sterile water for injection (SWFI) or a suitable buffer depending on the intended application. The product often comes with a detailed certificate of analysis (CoA) that lists critical parameters such as molecular weight, purity profile, and sterility test results.
When preparing KPV for experimental use, it is common to reconstitute each vial with 1 mL of SWFI to achieve a concentration of 1 mg/mL. From there, aliquots can be drawn into microcentrifuge tubes or syringes for storage at –20°C or –80°C if long-term usage is required. Because peptides are susceptible to degradation, it is recommended to keep the reconstituted solution in the dark and avoid repeated freeze–thaw cycles.
Dosing considerations
The 10 mg – 10 Vial Box allows flexibility in dosing regimens. For example, a researcher might use 0.1 mg per injection for a small animal study, giving them 100 injections from one box. In clinical contexts, doses of KPV have ranged from 50 µg to several milligrams per day, depending on the condition being treated and the route of administration (intravenous, subcutaneous, or oral). Because the peptide is rapidly cleared in vivo, multiple daily administrations may be necessary to maintain therapeutic levels.
Safety profile
KPV has generally been reported as safe in preclinical studies. Common adverse effects observed at high doses include mild injection site reactions or transient changes in blood pressure. However, long-term safety data are limited, and clinicians should monitor patients for any unexpected immune responses or allergic reactions. As with all peptide therapeutics, it is crucial to use a sterile preparation and adhere strictly to aseptic technique during handling.
Storage and shelf life
The lyophilized vials are stable at room temperature for up to 24 months when stored in a dry environment. Once reconstituted, the solution should be kept refrigerated or frozen, depending on the intended duration of use. The CoA will typically specify a recommended storage temperature, but most manufacturers advise storing the reconstituted peptide at –20°C and using aliquots within 48 hours to avoid degradation.
Applications in research
Scientists often employ KPV to dissect inflammatory pathways in vitro and in vivo. In cell culture models, adding KPV to neutrophil or macrophage preparations can suppress the release of reactive oxygen species and pro-inflammatory cytokines such as TNF-α and IL-6. In animal models of arthritis, repeated administration of KPV has been shown to reduce joint swelling and cartilage degradation. Researchers also use the peptide in studies of wound healing, where it may promote tissue repair by modulating local immune responses.
Ordering and regulatory considerations
When purchasing a 10 mg – 10 Vial Box of KPV, buyers should verify that the supplier complies with GMP standards and provides a comprehensive certificate of analysis. Depending on the jurisdiction, peptides used for therapeutic purposes may be regulated as investigational new drugs (IND) or require specific import permits. For academic research, many laboratories obtain KPV through university-approved vendors who provide the necessary documentation for compliance.
In summary, buying KPV peptide in a 10 mg – 10 Vial Box offers researchers and clinicians a versatile and high-quality product that can be used across a range of experimental and therapeutic contexts. The combination of GMP manufacturing, detailed quality control data, and convenient vial sizing makes it an attractive option for those exploring the anti-inflammatory potential of this promising tripeptide.